Since that meeting, the Blades have been relegated all the way up to the Premier League and back down into the Championship, while the Saints have established themselves in the top-flight ahead of tomorrow evening’s Carabao Cup third-round clash at Bramall Lane.
Here's where the Blades side from the memorable night at Bramall Lane ended up…
1. Mark Howard
Still holds the record for consecutive clean sheets for the Blades, with eight. Was released when Chris Wilder joined the Blades, and went onto play for Bolton and Blackpool. Later spent time on loan at Salford City and is now at Scunthorpe United Photo: MARTYN HARRISON
2. Ryan Flynn
The former Liverpool trainee joined United from Falkirk in his native Scotland and was a key member of the side that reached the FA Cup semi-final in 2014. After leaving United he went to Oldham before returning north of the border and joining St. Mirren Photo: GLYN KIRK
3. Chris Basham
The only player from the game still to be at United, Basham survived the Wilder cull and thrived in the right centre-half position. Now a regular in the Premier League and extended his stay at Bramall Lane further with another new contract in the summer Photo: OLI SCARFF
4. Jay McEveley
Partnering Basham at centre-half against Southampton, McEveley later became United's captain and, for some fans, the symbol of their struggles in League One. Was released by Wilder and dropped down the levels. In November, he was named head of academy coaching at Prestatyn Town Photo: Laurence Griffiths